Bad news, folks. Palatin (the company behind this drug) have released some trial results for PT-141, and things aren't looking as rosy as they have been. It's bad enough for their shares to fall by 10%. Chemgasm reports this informative comment from a post on the Yahoo finance forums:

This was supposed to be a N=560 and an N=250 trial.

They had to power it up to N=726 and N=294.

If they had not powered it up, they would have *MISSED*. Capice? The results were not as good as they were anticipating, so they added more subjects. OK?

There are *TWO* new side effects. One esophogeal tear. That is your throat ripping apart because you are vomiting so hard

More technical detail on the trials here