This was supposed to be a N=560 and an N=250 trial.
They had to power it up to N=726 and N=294.
If they had not powered it up, they would have *MISSED*. Capice? The results were not as good as they were anticipating, so they added more subjects. OK?
There are *TWO* new side effects. One esophogeal tear. That is your throat ripping apart because you are vomiting so hard
More technical detail on the trials here
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Oh, is that all? Just a little tear in your esophagus? That would just put me "in the mood".
Hey, stats are stats, and more data is generally not a bad thing. Lots of drugs have nausea and vomiting listed as side effects, it just sounds like somebody got a little too carried away. I'd say don't sell just yet.
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Bad news, folks. Palatin (the company behind this drug) have released some trial results for PT-141, and things aren't looking as rosy as they have been.
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