Saturday, October 28, 2006

What are the side effects of bremelanotide? The factsheet by Palatin (the makers of Pt-141) says they "include facial flushing, nausea, aftertaste and post-nasal drip". Headaches also get mentioned, particularly in women.

Chemgasm describes the flushing like this:

At 20 minutes post-dose, it peaked. Face had flushed scarlet red, my chest was somewhat red too, little pricks of red (allergy-like) appeared on my arms and chest and face. I experienced that hot-from-the-inside feeling one gets the night after being in the sun all day. Over the next ten-twenty minutes, the flush subsided.


All this might not sound so bad compared to, say, Viagra's "priapism, severe hypotension, myocardial infarction, ventricular arrhythmias, sudden death, stroke and increased intraocular pressure".

But remember that it's early days yet, and more side-effects are going to be coming out of the woodwork pretty soon.

2 comments:

Source of Information said...

Some of the side effects I read about include "severe nausea". This made me wonder if bremelanotide has some effect on dopamine receptors. Some D receptors are involved in erection, some are involved in nausea.

Also, the comparison with Viagra is not fair because drug companies are required by the FDA to include every side effect that showed up in clnical trials. Talk with any of the millions of men who have used Viagra, and they probably have the same experiences: some flushing, some nasal congestion, rare headaches.

To me, the big question with bremelanotide is not efficacy, but tolerability.

Chris said...

I love post-nasal drip. Might as well include halitosis and sore throat then.